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InChiKey: PRQROPMIIGLWRP-BZSNNMDCSA-N
Smiles: NCC(CC(O)=O)C1C=CC(Cl)=CC=1
4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)isonicotinamide
leads to dose-dependent tumor growth inhibition (TGI: 76% and 84% for 10 mg/kg and 30 mg/kg)
ML289 13767 InChiKey: PRQROPMIIGLWRP-BZSNNMDCSA-NML289 (VU0463597) is a potent, selective, and CNS penetrant mGlu3 (IC50=0. 66 M) negative allosteric modulator. ML289 displays >15 fold selectivity over mGlu2 and is inactive against mGlu5. Product information CAS Number: 1382481 79 9 Molecular Weight: 349. 42 Formula: C22H23NO3 Synonym: VU0463597 Chemical Name: [(3R) 1 {4 [2 (4 methoxyphenyl)ethynyl]benzoyl}piperidin 3 yl]methanol Smiles: COC1C=CC(=CC=1)C#CC1C=CC(=CC=1)C(=O)N1C[C@H](CO)CCC1 InChiKey:
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