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PubMed PMID: 27235137
Pulmonary actions of LY255283
GSK650394 inhibits the growth of LNCaP cells with IC50 of approximately 1 μM
CAS Number: 864082-47-3
TWS119 Size:10mg solid PubMed PMID: 27235137TWS 119 is a potent and selective inhibitor of glycogen synthase kinase 3 (IC50 = 30 nM). TWS119 could activate Wnt catenin pathway and up regulate the expression of CD62L in a dose dependent manner, but it decreased the expression of CD107a. Glycogen synthase kinase (GSK) 3, a constitutively active serine threonine kinase, acts as a key regulator of major signaling pathways, including the Wnt, Hedgehog, and Notch pathways. Product information CAS
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