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57% of viruses with genotypes containing Y181C as a single NNRTI mutation (43% for efavirenz)
GSK923295 has broad growth inhibitory activity in a panel of 237 cancer cell lines and produces significant tumor growth-delay in 8 of the 11 mouse xenograft tumor models with IC50s of 17
InChi: InChI=1S/C32H34ClN7O2/c1-4-12-40(26-9-7-24(8-10-26)31(41)35-20-23-6-5-11-34-19-23)21-25-17-27-29(18-28(25)33)36-30(38(3)32(27)42)22-39-15-13-37(2)14-16-39/h1
rat and mouse liver microsomes
c(phg-isoDGR-(NMe)k) ibrozil 57% of viruses with genotypesc(phg isoDGR (NMe)k) is a selective and potent 51 integrin ligand with an IC50 of 2. 9 nM. Product information CAS Number: 1844830 65 4 Molecular Weight: 603. 67 Formula: C27H41N9O7 Chemical Name: (5S,8R,11R,14S) 8 (4 aminobutyl) 5 (3 carbamimidamidopropyl) 7 methyl 3,6,9,12,16 pentaoxo 11 phenyl 1,4,7,10,13 pentaazacyclohexadecane 14 carboxylic acid Smiles: