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2016 May 1
01-1 μM) also increases intracellular cAMP in lung fibroblasts
pii: S0006-291X(17)31704-7
In BALB/c mice bearing hepatic fibrosis
Imatinib Impurity E PEG3-amine-Boc 2016 May 1Imatinib Impurity E is the impurity of Imatinib. Imatinib is an orally bioavailable tyrosine kinases inhibitor that selectively inhibits BCR ABL, v Abl, PDGFR and c kit kinase activity. Imatinib (STI571) works by binding close to the ATP binding site, locking it in a closed or self inhibited conformation, therefore inhibiting the enzyme activity of the protein semicompetitively. Imatinib also is an inhibitor of SARS CoV and MERS CoV. Product
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