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5S)-2-hydrogenio-2-{[(2R
3-h]quinazoline-3-carboxamide
Median overall survival of treated animals (TAS-116
InChi: InChI=1S/C24H25FN6O
MS417 Catalog No.:M14631-2 5S)-2-hydrogenio-2-{[(2RMS417 is a selective BET specific BRD4 inhibitor, binds to BRD4 BD1 and BRD4 BD2 with IC50s of 30, 46 nM and Kds of 36. 1, 25. 4 nM, respectively, with weak selectivity at CBP BRD (IC50, 32. 7 M). Product information CAS Number: 916489 36 6 Molecular Weight: 414. 91 Formula: C20H19ClN4O2S Chemical Name: methyl 2 [(9S) 7 (4 chlorophenyl) 4,5,13 trimethyl 3 thia 1,8,11,12 tetraazatricyclo[8. 3. 0. 0,]trideca 2(6),4,7,10,12 pentaen 9 yl]acetate Smiles:
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